Endocrine Abstracts

Abstract: The secondary adrenal insufficiency (SAI) is life-threatening disease. 30–50% of patients have SAI following craniospinal irradiation (CSI). The “gold standard” of SAI diagnosis is the insulin tolerance test but it is demanding for patient and medical staff. The simple and reliable test would allow to use ITT rarely. The aim was to evaluate probability of using DHEA-S in SAI diagnosis. 41 patient after CSI non-pituitary brain tumors survivor and 23 hea...